MASP1 antibody

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MASP1 antibody

CAT:

710-FNab05021

Size:

100 µg

Price:

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For price, please contact [email protected].

Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin(MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Synonyms: Mannan-binding lectin serine protease 1|Complement factor MASP-3|Complement-activating component of Ra-reactive factor|Mannose-binding lectin-associated serine protease 1 (MASP-1)|Mannose-binding protein-associated serine protease|Ra-reactive factor serine protease p100 (RaRF)|Serine protease 5|Mannan-binding lectin serine protease 1 heavy chain|Mannan-binding lectin serine protease 1 light chain|MASP1|CRARF|CRARF1|PRSS5
Gene ID: 5648
UniProt: P48740
Host: Rabbit
Reactivity: Human
Immunogen: mannan-binding lectin serine peptidase 1(C4/C2 activating component of Ra-reactive factor)
Target: MASP1
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA, WB
Field of Research: Metabolism
Purification: Immunogen affinity purified
Dilution: WB: 1:500-1:2000
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular Weight: 40-70 kDa
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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