MARK3 antibody

• Background:

  Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.

• Synonyms:

  MAP/microtubule affinity-regulating kinase 3|C-TAK1 (cTAK1) |Cdc25C-associated protein kinase 1|ELKL motif kinase 2 (EMK-2) |Protein kinase STK10|Ser/Thr protein kinase PAR-1 (Par-1a) |Serine/threonine-protein kinase p78|MARK3|CTAK1|EMK2

• Gene ID:

  4140

• UniProt:

  P27448

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  MAP/microtubule affinity-regulating kinase 3

• Target:

  MARK3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Neuroscience, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  80-90 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB