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MARCKSL1 antibody

CAT: 0710-FNab05010Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05010Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity) .
Synonyms
MARCKS-related protein|MARCKS-like protein 1|Macrophage myristoylated alanine-rich C kinase substrate (Mac-MARCKS, MacMARCKS) |MARCKSL1|MLP|MRP
UniProt
P49006
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
MARCKS-like 1
Target
MARCKSL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40-50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P49006

MARCKS-related protein

MRP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49006
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MARCKSL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D3DPQ0, Q5TEE6, Q6NXS5
Protein keywords

Molecular function

Actin-bindingCalmodulin-binding

Cellular component

Cell membraneCytoplasmCytoskeletonMembrane

PTM

LipoproteinMyristatePhosphoprotein

Technical term

Proteomics identificationReference proteome

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