MAP1B antibody

• Background:

  Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity) . Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

• Synonyms:

  Microtubule-associated protein 1B (MAP-1B) |MAP1B heavy chain|MAP1 light chain LC1|MAP1B

• Gene ID:

  4131

• UniProt:

  P46821

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Microtubule-associated protein 1B

• Target:

  MAP1B

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, FC, IF

• Field of Research:

  Neuroscience

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  320 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, FC, IF