PSMB9 antibody

CAT: 0710-FNab04810Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab04810Size:100 µg
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
Synonyms
Proteasome subunit beta type-9|Low molecular mass protein 2|Macropain chain 7|Multicatalytic endopeptidase complex chain 7|Proteasome chain 7|Proteasome subunit beta-1i|Really interesting new gene 12 protein|PSMB9|LMP2|PSMB6i|RING12
Gene ID
5698
UniProt
P28065
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
Target
PSMB9
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP, IF
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21-23 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP, IF

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