LIPA antibody

CAT: 0710-FNab04793Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab04793Size:100 µg
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Background
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Synonyms
Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase, LAL) |Cholesteryl esterase|Lipase A|Sterol esterase|LIPA
Gene ID
3988
UniProt
P38571
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Lipase A, lysosomal acid, cholesterol esterase
Target
LIPA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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