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LGR6 antibody

CAT: 0710-FNab04766Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04766Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Synonyms
Leucine-rich repeat-containing G-protein coupled receptor 6|LGR6
Gene ID
59352
UniProt
Q9HBX8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Leucine-rich repeat-containing G protein-coupled receptor 6
Target
LGR6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, FC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
104 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, FC

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