LC3 antibody

• Background:

  Map1LC3, also known as LC3, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. Three human Map1LC isoforms, MAP1LC3A, MAP1LC3B, and MAP1LC3C, undergo post-translational modifications during autophagy. And they differ in their post-translation modifications during autophagy. Map1LC3 also exists in two modified forms, an 18-kDa cytoplasmic form that was originally identified as a subunit of the microtubule-associated protein 1, and a 16-kDa form that is associated with the autophagosome membrane. This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C.

• Synonyms:

  Microtubule-associated proteins 1A/1B light chain 3B|Autophagy-related protein LC3 B|Autophagy-related ubiquitin-like modifier LC3 B|MAP1 light chain 3-like protein 2|MAP1A/MAP1B light chain 3 B (MAP1A/MAP1B LC3 B) |Microtubule-associated protein 1 light chain 3 beta|MAP1LC3B|MAP1ALC3

• Gene ID:

  81631

• UniProt:

  Q9GZQ8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Microtubule-associated protein 1 light chain 3 beta

• Target:

  LC3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Neuroscience, Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  16 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.1% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP

• Immunogen Sequence:

  1-125aa