LMNB1 antibody

• Background :

  Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.

• Synonyms :

  Lamin-B1|LMNB1|LMN2|LMNB

• Gene ID :

  4001

• UniProt :

  P20700

• Host :

  Mouse

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Lamin B1

• Target :

  LMNB1

• Clonality :

  Monoclonal

• Isotype :

  IgG2a

• Applications :

  ELISA, WB, IF, FC, IP

• Field of Research :

  Stem Cells, Developmental biology

• Purification :

  Protein A+G purification

• Dilution :

  WB: 1:500-1:2000; IP: 1:5000-1:50000 ; IHC: 1:500-1:2000; IF: 1:50-1:500

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  66 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID :

  4A4

• Tested Applications :

  ELISA, WB, IF, FC, IP