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L2HGDH antibody

CAT: 0710-FNab04670Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04670Size:100 µg
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Background
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
Synonyms
L-2-hydroxyglutarate dehydrogenase, mitochondrial|Duranin|L2HGDH|C14orf160
Gene ID
79944
UniProt
Q9H9P8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
L-2-hydroxyglutarate dehydrogenase
Target
L2HGDH
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDaa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q9H9P8

L-2-hydroxyglutarate dehydrogenase, mitochondrial

L2HDH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H9P8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
L2HGDH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.1.99.2
Processing
Precursor
Secondary accessions
Q9BRR1
Protein keywords

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Ligand

FADFlavoprotein

Cellular component

Mitochondrion

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

Transit peptide

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