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KPNA1 antibody

CAT: 0710-FNab04634Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04634Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
Synonyms
Importin subunit alpha-5|Karyopherin subunit alpha-1|Nucleoprotein interactor 1 (NPI-1) |RAG cohort protein 2|SRP1-beta|Importin subunit alpha-5, N-terminally processed|KPNA1|RCH2
Gene ID
3836
UniProt
P52294
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Karyopherin alpha 1 (importin alpha 5)
Target
KPNA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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