Products for Research Use Only
RegisterLogin

KLHL12 antibody

CAT: 0710-FNab04610Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab04610Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR (KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR (KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B) . As part of the BCR (KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3. The BCR (KLHL12) complex also mediates polyubiquitination of DRD4, without leading to degradation of DRD4.
Synonyms
Kelch-like protein 12|CUL3-interacting protein 1|DKIR homolog (hDKIR) |KLHL12|C3IP1
Gene ID
59349
UniProt
Q53G59
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Kelch-like 12 (Drosophila)
Target
KLHL12
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53-56 kDa, 63-67 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

Related Products

CatalogName
P5937-01Recombinant Human KLHL12
EH9656Human KLHL12 (Kelch-like protein 12) ELISA Kit
EH4743Human Anti-KLHL12 (anti-Kelch-like protein 12 antibody) ELISA Kit
QT-EH9656Human KLHL12 (Kelch-like protein 12) QuickTest ELISA Kit
FNab04625KLHL32 antibody
FNab04619KLHL21 antibody
FNab04608KLHL42 antibody
FNab04609KLHL10 antibody
FNab04612KLHL14 antibody
FNab04616KLHL18 antibody

Alternative Products

CatalogName
GTR18161714-01KLHL12 Antibody

Popular Products