KIRREL3 antibody

CAT: 0710-FNab04591Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab04591Size:100 µg
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Background
Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells.
Synonyms
Kin of IRRE-like protein 3|Kin of irregular chiasm-like protein 3|Nephrin-like protein 2|Processed kin of IRRE-like protein 3|KIRREL3|KIAA1867|NEPH2
Gene ID
84623
UniProt
Q8IZU9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Kin of IRRE like 3 (Drosophila)
Target
KIRREL3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
125 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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