KEAP1 antibody

• Background:

  This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

• Synonyms:

  Kelch-like ECH-associated protein 1|Cytosolic inhibitor of Nrf2 (INrf2) |Kelch-like protein 19|KEAP1|INRF2|KIAA0132|KLHL19

• Gene ID:

  9817

• UniProt:

  Q14145

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Kelch-like ECH-associated protein 1

• Target:

  KEAP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC, IF, WB

• Field of Research:

  Cancer, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  55-80 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC, IF, WB

• Immunogen Sequence:

  378-486aa