KCNN4 antibody

• Background:

  Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).

• Synonyms:

  Intermediate conductance calcium-activated potassium channel protein 4 (SK4, SKCa 4, SKCa4)|IKCa1 (IK1)|KCa3.1|KCa4|Putative Gardos channel|KCNN4|IK1|IKCA1|KCA4|SK4

• Gene ID:

  3783

• UniProt:

  O15554

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

• Target:

  KCNN4

• Clonality:

  Monoclonal

• Isotype:

  IgG2a

• Clone:

  8A11

• Applications:

  ELISA, WB

• Field of Research:

  Neuroscience, Developmental biology

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:500 - 1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  48 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4