KCNN4 antibody

• Background :

  Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990) . Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614) .

• Synonyms :

  Intermediate conductance calcium-activated potassium channel protein 4 (SK4, SKCa 4, SKCa4) |IKCa1 (IK1) |KCa3.1|KCa4|Putative Gardos channel|KCNN4|IK1|IKCA1|KCA4|SK4

• Gene ID :

  3783

• UniProt :

  O15554

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

• Target :

  KCNN4

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Neuroscience, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  48 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB

• Immunogen Sequence :

  292-427aa