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KCNJ5 antibody

CAT: 0710-FNab04493Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04493Size:100 µg
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Background
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Synonyms
G protein-activated inward rectifier potassium channel 4 (GIRK-4) |Cardiac inward rectifier (CIR) |Heart KATP channel|Inward rectifier K (+) channel Kir3.4 (IRK-4) |KATP-1|Potassium channel, inwardly rectifying subfamily J member 5|KCNJ5|GIRK4
Gene ID
3762
UniProt
P48544
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Potassium inwardly-rectifying channel, subfamily J, member 5
Target
KCNJ5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P48544

G protein-activated inward rectifier potassium channel 4

KCNJ5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48544
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KCNJ5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GIRK-4
EC number
—
Processing
—
Secondary accessions
B2R744, Q6DK13, Q6DK14, Q92807
Protein keywords

Disease

Disease variantLong QT syndrome

Molecular function

Ion channelVoltage-gated channel

Biological process

Ion transportPotassium transportTransport

Cellular component

Membrane

PTM

Phosphoprotein

Ligand

Potassium

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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