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KCNIP3 antibody

CAT: 0710-FNab04488Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04488Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity) . Regulatory subunit of Kv4/D (Shal) -type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of beta-amyloid formation.
Synonyms
Calsenilin|A-type potassium channel modulatory protein 3|DRE-antagonist modulator (DREAM) |Kv channel-interacting protein 3 (KChIP3) |KCNIP3|CSEN|DREAM|KCHIP3
Gene ID
30818
UniProt
Q9Y2W7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Kv channel interacting protein 3, calsenilin
Target
KCNIP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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