JPH2 antibody

• Background:

  Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca (2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.

• Synonyms:

  Junctophilin-2 (JP-2) |Junctophilin type 2|Junctophilin-2 N-terminal fragment (JP2NT) |JPH2|JP2

• Gene ID:

  57158

• UniProt:

  Q9BR39

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Junctophilin 2

• Target:

  JPH2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IHC

• Field of Research:

  Neuroscience

• Purification:

  Immunogen affinity purified

• Dilution:

  IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IHC