Products for Research Use Only
RegisterLogin

IPO11 antibody

CAT: 0710-FNab04373Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab04373Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity) . Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity) .
Synonyms
Importin-11 (Imp11) |Ran-binding protein 11 (RanBP11) |IPO11|RANBP11
Gene ID
51194
UniProt
Q9UI26
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Importin 11
Target
IPO11
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
112 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

Related Products

CatalogName
P8872-01Recombinant Human IPO11
FNab04374IPO13 antibody
FNab11062CA125 antibody (capture antibody)
FNab11060AFP antibody (capture antibody)
FNab11045-01CEA antibody (detection antibody)
FNab11061CA125 antibody (detection antibody)
FNab11059AFP antibody (detection antibody)
FNab11046-01CEA antibody (capture antibody)
FNab09471WAS antibody
FNab11063CA19-9 antibody (detection antibody)

Alternative Products

CatalogName
70R-17998IPO11 antibody
MBS2562690-01IPO11 Polyclonal Antibody
39613Anti-IPO11 Antibody
565824-01IPO11

Popular Products