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INS antibody

CAT: 0710-FNab04339Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04339Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A-and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in insulin results in type 1 diabetes mellitus. Insulin may also exist 36 kDa form corresponding to the hexameric insulin form.
Synonyms
Insulin|Insulin B chain|Insulin A chain|INS
Gene ID
3630
UniProt
P01308
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Insulin
Target
INS
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IHC
Field of Research
Signal Transduction, Metabolism, Immunology, Cancer, Stem Cells
Purification
Protein A+G purification
Dilution
IHC: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
0H2
Tested Applications
ELISA, IHC
Immunogen Sequence
1-110aa

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