INO80 antibody

CAT: 0710-FNab04323Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab04323Size:100 µg

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Background

DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.

Synonyms

Gene ID

54617

UniProt

Q9ULG1

Host

Rabbit

Reactivity

Human

Immunogen

INO80 homolog

Target

INO80

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

177, 150 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IP

UniProtKB · Q9ULG1

Chromatin-remodeling ATPase INO80

INO80_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9ULG1
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: INO80
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: hINO80
EC number: 3.6.4.-
Processing: —
Secondary accessions: A6H8X4, Q9NTG6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

Actin-bindingDNA-bindingHydrolase

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell divisionDNA damageDNA recombinationDNA repairHost-virus interactionMitosis

Cellular component

ChromosomeCytoplasmCytoskeletonMicrotubuleNucleus

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Alternative Products

Catalog	Name
abx234322	DNA Helicase INO80 (INO80) Antibody
A26331-100UL	INO80 Antibody