ING4 antibody

CAT: 0710-FNab04313Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab04313Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) . Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity) .
Synonyms
Inhibitor of growth protein 4|p29ING4|ING4
Gene ID
51147
UniProt
Q9UNL4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Inhibitor of growth family, member 4
Target
ING4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

Related Products

CatalogName
FNab04314ING4-specific antibody
P1275-01Recombinant Human ING4
FNab04308ING1 antibody
FNab04310ING2 antibody
FNab04311ING3 antibody
FNab04315ING5 antibody
FNab10753ING2 antibody
FNab04312ING3-specific antibody
FNab04309ING1-specific antibody
P1347-01Recombinant Human ING3

Alternative Products

CatalogName
MBS858191-01ING4 Antibody

Popular Products