IMPDH2 antibody

• Background:

  Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

• Synonyms:

  Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2, IMPD 2, IMPDH 2) |Inosine-5'-monophosphate dehydrogenase type II (IMP dehydrogenase II, IMPDH-II) |IMPDH2|IMPD2

• Gene ID:

  3615

• UniProt:

  P12268

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  IMP (inosine monophosphate) dehydrogenase 2

• Target:

  IMPDH2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  56 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF, IP