IMPDH2 antibody

• Background :

  Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

• Synonyms :

  Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2, IMPD 2, IMPDH 2) |Inosine-5'-monophosphate dehydrogenase type II (IMP dehydrogenase II, IMPDH-II) |IMPDH2|IMPD2

• Gene ID :

  3615

• UniProt :

  P12268

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  IMP (inosine monophosphate) dehydrogenase 2

• Target :

  IMPDH2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF, IP

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  56 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF, IP