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ILF3 antibody

CAT: 0710-FNab04288Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04288Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Synonyms
Interleukin enhancer-binding factor 3|Double-stranded RNA-binding protein 76 (DRBP76) |M-phase phosphoprotein 4 (MPP4) |Nuclear factor associated with dsRNA (NFAR) |Nuclear factor of activated T-cells 90 kDa (NF-AT-90) |Translational control protein 80 (TCP80) |ILF3|DRBF|MPHOSPH4|NF90
Gene ID
3609
UniProt
Q12906
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Interleukin enhancer binding factor 3, 90kDa
Target
ILF3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
95/120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

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