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IFT57 antibody

CAT: 0710-FNab04160Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04160Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity) . Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Synonyms
Intraflagellar transport protein 57 homolog|Dermal papilla-derived protein 8|Estrogen-related receptor beta-like protein 1|HIP1-interacting protein|MHS4R2|IFT57|DERP8|ESRRBL1|HIPPI
Gene ID
55081
UniProt
Q9NWB7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Intraflagellar transport 57 homolog (Chlamydomonas)
Target
IFT57
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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