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ICAM1 antibody

CAT: 0710-FNab04103Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04103Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690) . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056) . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784) .
Synonyms
Intercellular adhesion molecule 1 (ICAM-1) |Major group rhinovirus receptor|ICAM1
Gene ID
3383
UniProt
P05362
Host
Mouse
Reactivity
Human
Immunogen
Intercellular adhesion molecule 1
Target
ICAM1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, IHC, WB, FC
Field of Research
Stem Cells, Immunology, Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:4000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85-95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7F11
Tested Applications
ELISA, IHC, WB, FC
Immunogen Sequence
200-532aa

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