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ICAM1 antibody

CAT: 0710-FNab04102Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab04102Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690) . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056) .
Synonyms
Intercellular adhesion molecule 1 (ICAM-1) |Major group rhinovirus receptor|ICAM1
Gene ID
3383
UniProt
P05362
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Intercellular adhesion molecule 1
Target
ICAM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF, WB, IHC, IP
Field of Research
Stem Cells, Immunology, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85-95 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF, WB, IHC, IP
Immunogen Sequence
26-272aa

UniProtKB · P05362

Intercellular adhesion molecule 1

ICAM1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05362
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ICAM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ICAM-1
EC number
—
Processing
Precursor
Secondary accessions
B2R6M3, Q5NKV7, Q96B50
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Cell adhesionHost-virus interaction

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

Host cell receptor for virus entryReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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