HOMER2 antibody

• Background :

  Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (PubMed:9808459) . Required for normal hearing (PubMed:25816005) .

• Synonyms :

  Homer protein homolog 2 (Homer-2) |Cupidin|HOMER2

• Gene ID :

  9455

• UniProt :

  Q9NSB8

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Homer homolog 2 (Drosophila)

• Target :

  HOMER2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  39 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB