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HJURP antibody

CAT: 0710-FNab03892Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03892Size:100 µg
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Background
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Synonyms
Holliday junction recognition protein|14-3-3-associated AKT substrate|Fetal liver-expressing gene 1 protein|Up-regulated in lung cancer 9|HJURP|FAKTS|FLEG1|URLC9
Gene ID
55355
UniProt
Q8NCD3
Host
Rabbit
Reactivity
Human
Immunogen
Holliday junction recognition protein
Target
HJURP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa, 83-85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

UniProtKB · Q8NCD3

Holliday junction recognition protein

HJURP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NCD3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HJURP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8IRH5, B4DWR0, B4DZV4, Q9BUT2, Q9NSL8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycle

Cellular component

CentromereChromosomeNucleus

Molecular function

ChaperoneDNA-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

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