HERC4 antibody

• Background:

  Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.

• Synonyms:

  Probable E3 ubiquitin-protein ligase HERC4|HECT domain and RCC1-like domain-containing protein 4|HECT-type E3 ubiquitin transferase HERC4|HERC4|KIAA1593

• UniProt:

  Q5GLZ8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Hect domain and RLD 4

• Target:

  HERC4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Epigenetics, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  107 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF