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HARS2 antibody

CAT: 0710-FNab03759Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03759Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.
Synonyms
Histidine--tRNA ligase, mitochondrial|Histidine--tRNA ligase-like|Histidyl-tRNA synthetase (HisRS) |HARS2|HARSL|HARSR|HO3
Gene ID
23438
UniProt
P49590
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Histidyl-tRNA synthetase 2, mitochondrial (putative)
Target
HARS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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