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MACROH2A2 antibody

CAT: 0710-FNab03739Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03739Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Synonyms
Core histone macro-H2A.2 (Histone macroH2A2, mH2A2) |MACROH2A2|H2AFY2
Gene ID
55506
UniProt
Q9P0M6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
H2A histone family, member Y2
Target
MACROH2A2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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