GP repeat antibody

• Background:

  The C9orf72 "GGGGCC" repeat sequence codes five repeat peptide "GA repeat; GAGAGAGAGA", "GP repeat; GPGPGPGPG", "GR repeat; GRGRGRGRG", "AP repeat; APAPAPAPA" and "PR repeat; PRPRPRPRP". It was described previously that aggregated forms of poly-GA and poly-GP proteins do not enter the separation gel (PMID: 26374446) . This antibody is used to detect the GP repeated sequence. The recombinant protein with 6*His tag or GST tag which contains the sequence “GPGPGPGPG” were used to detect this antibody.

• Synonyms:

  C9RAN|GGGCC|GP repeat|GPGPGPGP|poly GP|poly PG

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  GP repeat

• Target:

  GP repeat

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC