GP repeat antibody

• Background :

  The C9orf72 "GGGGCC" repeat sequence codes five repeat peptide "GA repeat; GAGAGAGAGA", "GP repeat; GPGPGPGPG", "GR repeat; GRGRGRGRG", "AP repeat; APAPAPAPA" and "PR repeat; PRPRPRPRP". It was described previously that aggregated forms of poly-GA and poly-GP proteins do not enter the separation gel (PMID: 26374446) . This antibody is used to detect the GP repeated sequence. The recombinant protein with 6*His tag or GST tag which contains the sequence “GPGPGPGPG” were used to detect this antibody.

• Synonyms :

  C9RAN|GGGCC|GP repeat|GPGPGPGP|poly GP|poly PG

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  GP repeat

• Target :

  GP repeat

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC