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GNRHR antibody

CAT: 0710-FNab03555Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03555Size:100 µg
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Background
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) . This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Synonyms
Gonadotropin-releasing hormone receptor (GnRH receptor, GnRH-R) |GNRHR|GRHR
Gene ID
2798
UniProt
P30968
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Gonadotropin-releasing hormone receptor
Target
GNRHR
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IP
Field of Research
Neuroscience, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IP

UniProtKB · P30968

Gonadotropin-releasing hormone receptor

GNRHR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30968
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GNRHR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GnRH receptor, GnRH-R
EC number
—
Processing
—
Secondary accessions
O75793, Q14D13, Q92644
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Disease variantHypogonadotropic hypogonadism

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix

Alternative Products