GNB5 antibody

CAT: 0710-FNab03543Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab03543Size:100 µg
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Background
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Synonyms
Guanine nucleotide-binding protein subunit beta-5|Gbeta5|Transducin beta chain 5|GNB5
Gene ID
10681
UniProt
O14775
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Guanine nucleotide binding protein (G protein), beta 5
Target
GNB5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
39-42 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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