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GNAQ antibody

CAT: 0710-FNab03535Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03535Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity) .
Synonyms
Guanine nucleotide-binding protein G (q) subunit alpha|Guanine nucleotide-binding protein alpha-q|GNAQ|GAQ
Gene ID
2776
UniProt
P50148
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Guanine nucleotide binding protein (G protein), q polypeptide
Target
GNAQ
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
1-359

UniProtKB · P50148

Guanine nucleotide-binding protein G(q) subunit alpha

GNAQ_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P50148
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GNAQ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.-
Processing
—
Secondary accessions
O15108, Q13462, Q6NT27, Q92471, Q9BZB9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationLipoproteinPalmitate

Cellular component

Cell membraneGolgi apparatusMembraneNucleus

Disease

Disease variant

Ligand

GTP-bindingMagnesiumMetal-bindingNucleotide-binding

Molecular function

HydrolaseTransducer

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