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GLRA3 antibody

CAT: 0710-FNab03488Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03488Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:9677400, PubMed:26416729) . Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (By similarity) . Plays an important role in the down-regulation of neuronal excitability (By similarity) . Contributes to the generation of inhibitory postsynaptic currents (By similarity) . Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity) . Plays a role in cellular responses to ethanol (By similarity) .
Synonyms
Glycine receptor subunit alpha-3|GLRA3
Gene ID
8001
UniProt
O75311
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Glycine receptor, alpha 3
Target
GLRA3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
54 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB