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GDI1 antibody

CAT: 0710-FNab03404Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03404Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
Synonyms
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) |Guanosine diphosphate dissociation inhibitor 1 (GDI-1) |Oligophrenin-2|Protein XAP-4|GDI1|GDIL|OPHN2|RABGDIA|XAP4
Gene ID
2664
UniProt
P31150
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
GDP dissociation inhibitor 1
Target
GDI1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P31150

Rab GDP dissociation inhibitor alpha

GDIA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31150
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GDI1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Rab GDI alpha
EC number
—
Processing
—
Secondary accessions
P50394, Q6FG50, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6
Protein keywords

Cellular component

CytoplasmGolgi apparatus

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variantIntellectual disability

Molecular function

GTPase activation

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