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G3BP1 antibody

CAT: 0710-FNab03267Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03267Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP-and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'-and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Synonyms
Ras GTPase-activating protein-binding protein 1 (G3BP-1) |ATP-dependent DNA helicase VIII (hDH VIII) |GAP SH3 domain-binding protein 1|G3BP1|G3BP
Gene ID
10146
UniProt
Q13283
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
GTPase activating protein (SH3 domain) binding protein 1
Target
G3BP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IF, IHC, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IF, IHC, FC

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