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FKBP5 antibody

CAT: 0710-FNab03141Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03141Size:100 µg
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Background
Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
Synonyms
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) |51 kDa FK506-binding protein (51 kDa FKBP, FKBP-51) |54 kDa progesterone receptor-associated immunophilin|Androgen-regulated protein 6|FF1 antigen|FK506-binding protein 5 (FKBP-5) |FKBP54 (p54) |HSP90-binding immunophilin|Rotamase|FKBP5|AIG6|FKBP51
Gene ID
2289
UniProt
Q13451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
FK506 binding protein 5
Target
FKBP5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
51 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

UniProtKB · Q13451

Peptidyl-prolyl cis-trans isomerase FKBP5

FKBP5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13451
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FKBP5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PPIase FKBP5
EC number
5.2.1.8
Processing
—
Secondary accessions
F5H7R1, Q59EB8, Q5TGM6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

ChaperoneIsomeraseRotamase

Cellular component

CytoplasmNucleus

Domain

RepeatTPR repeat

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