FGFR2 antibody

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
CSB-PA449267-02	FGFR2 Antibody
MBS9613860-02	FGFR2 Antibody
MBS9600097-02	FGFR2 Antibody
AF6839-02	FGFR2 Antibody
CSB-PA008645LA01HU-01	FGFR2 Antibody
MBS7127136-02	FGFR2 Antibody
MBS7136486-02	FGFR2 Antibody
MBS830409-01	FGFR2 antibody
MBS838579-01	FGFR2 antibody
MBS8501901-01	FGFR2 Antibody

FGFR2 antibody

CAT:

710-FNab03102

Size:

100 µg

Price:

Ask

For price, please contact [email protected].

Background: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.
Synonyms: Fibroblast growth factor receptor 2 (FGFR-2)|K-sam (KGFR)|Keratinocyte growth factor receptor|FGFR2|BEK|KGFR|KSAM
Gene ID: 2263
UniProt: P21802
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: fibroblast growth factor receptor 2
Target: FGFR2
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA, WB, IF
Field of Research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience, Stem Cells
Purification: Immunogen affinity purified
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular Weight: 120 kDa, 85-92 kDa
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Complementary Product Range

Our range of products, including FGFR2 antibody, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
FNab03102	FGFR2 antibody
FNab09802	Phospho-FGFR2 (ser782) Antibody
Pr22555-02	Recombinant Human FGFR2 alpha
Pr22555-04	Recombinant Human FGFR2 alpha
Pr22555-03	Recombinant Human FGFR2 alpha
Pr22555-01	Recombinant Human FGFR2 alpha
EH3060	Human FGFR2 (Fibroblast Growth Factor Receptor 2) ELISA Kit
FNab10672	Phospho-EIF2S1 (Ser51) antibody antibody
FNab010697	ASCL1 antibody
FNab010698	HES1 antibody