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FBXO22 antibody

CAT: 0710-FNab03041Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab03041Size:100 µg
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Background
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.
Synonyms
F-box only protein 22|F-box protein FBX22p44|FBXO22|FBX22
Gene ID
26263
UniProt
Q8NEZ5
Host
Rabbit
Reactivity
Human
Immunogen
F-box protein 22
Target
FBXO22
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q8NEZ5

F-box only protein 22

FBX22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NEZ5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FBXO22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q0D2P8, Q6PIL5, Q8IXW3, Q9H824, Q9UKC0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

Ubl conjugation pathway

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