FASN antibody

• Background:

  The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

• Synonyms:

  Fatty acid synthase|Type I fatty acid synthase|FASN|FAS

• Gene ID:

  2194

• UniProt:

  P49327

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Fatty acid synthase

• Target:

  FASN

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IF, IHC, WB

• Field of Research:

  Cancer, Cardiovascular, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  280 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IF, IHC, WB