ERK1/2 antibody

• Background :

  ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF. This antibody can recognize both ERK1 and ERK2 with the molecular mass of 38-44 kDa.

• Synonyms :

  Mitogen-activated protein kinase 1 (MAP kinase 1, MAPK 1) |ERT1|Extracellular signal-regulated kinase 2 (ERK-2) |MAP kinase isoform p42 (p42-MAPK) |Mitogen-activated protein kinase 2 (MAP kinase 2, MAPK 2) |MAPK1|ERK2|PRKM1|PRKM2

• Gene ID :

  5594

• UniProt :

  P28482

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Mitogen-activated protein kinase 1

• Target :

  ERK1/2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience, Cell Division and Proliferation

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:10-1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  38-44 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF