ELL antibody

CAT: 0710-FNab02740Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02740Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780) . Specifically required for stimulating the elongation step of RNA polymerase II-and III-dependent snRNA gene transcription (PubMed:23932780) . ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
Synonyms
RNA polymerase II elongation factor ELL|Eleven-nineteen lysine-rich leukemia protein|ELL|C19orf17
Gene ID
8178
UniProt
P55199
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Elongation factor RNA polymerase II
Target
ELL
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68-80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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