Products for Research Use Only
RegisterLogin

DYNLT1 antibody

CAT: 0710-FNab02590Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab02590Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation (By similarity) .
Synonyms
Dynein light chain Tctex-type 1|Protein CW-1|T-complex testis-specific protein 1 homolog|DYNLT1|TCTEL1|TCTEX-1|TCTEX1
Gene ID
6993
UniProt
P63172
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Dynein, light chain, Tctex-type 1
Target
DYNLT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

Related Products

CatalogName
P5536-01Recombinant Human DYNLT1
FNab02591DYNLT3 antibody
FNab02589DYNLRB1 antibody
FNab02588DYNLL2 antibody
P5335-01Recombinant Human DYNLT3
P5535-01Recombinant Human DYNLL1
P9531-01Recombinant Human DYNLL2
P6744-01Recombinant Human DYNLRB1
FNab11062CA125 antibody (capture antibody)
FNab11061CA125 antibody (detection antibody)

Alternative Products

CatalogName
70R-16968DYNLT1 antibody
BS78525-01DYNLT1 polyclonal antibody
MBS9453901-01DYNLT1 Conjugated Antibody
FY12554DYNLT1 Antibody / TCTEX1
PAab02590Anti-DYNLT1 antibody
bsm-62772R-01DYNLT1 Recombinant Antibody
522423-01DYNLT1

Popular Products