DOK4 antibody

CAT: 0710-FNab02503Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02503Size:100 µg
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Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity) . Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Synonyms
Docking protein 4|Downstream of tyrosine kinase 4|Insulin receptor substrate 5 (IRS-5, IRS5) |DOK4
Gene ID
55715
UniProt
Q8TEW6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Docking protein 4
Target
DOK4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Neuroscience, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

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