DNASE2 antibody

• Background:

  Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

• Synonyms:

  Deoxyribonuclease-2-alpha|Acid DNase|Deoxyribonuclease II alpha (DNase II alpha) |Lysosomal DNase II|R31240_2|DNASE2|DNASE2A|DNL2

• Gene ID:

  1777

• UniProt:

  O00115

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Deoxyribonuclease II, lysosomal

• Target:

  DNASE2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  32 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB