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DLD antibody

CAT: 0710-FNab02406Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02406Size:100 µg
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Background
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.
Synonyms
Dihydrolipoyl dehydrogenase, mitochondrial|Dihydrolipoamide dehydrogenase|Glycine cleavage system L protein|DLD|GCSL|LAD|PHE3
Gene ID
1738
UniProt
P09622
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Dihydrolipoamide dehydrogenase
Target
DLD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
54 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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